名师简介
姓名：赵明 性别：女 职称：教授 职务：副院长 招生院所：化学生物学与药学院 招生类型：科学学位(博) 科学学位(硕) 招生专业：神经生物学(博) 药物化学(硕) 研究方向名称：甾体缀合物的药物研究 电子信箱： 社会任职 1. 北京市药学会药化专业研究室副主任 个人简历 重要学术论文 1. Ming Zhao, Zheng Li, Yihui Wu, Chao Wang, Ziding Zhang, Shiqi Peng*.Studies on LogP, Retention Time and QSAR of 2-Substitutedphenylnitronyl Nitroxides as Free Radical Scavenger. Eur. J. Med. Chem.. 2007,42:955-965.SCI 2. Ming Zhao, Zheng Li, Li Peng, Yu-Rong Tang, Chao Wang, Ziding Zhang, Shiqi Peng*.Novel 1-Oxyl-2-substitutedphenyl-4,4,5,5-tetramethylimidazolines: Synthesis, Selectively Analgesic Action and QSAR analysis. Bioorg. Med. Chem. . 2007,15:2815-2826.SCI 3. Ming Zhao, Xin Jia, Chao Wang, Qin Li, Kexiang Zhou, Lili Wang, Hu Liu and Shiqi Peng*.PAK: An Essential Motif for Forming β-Turn Structures and Exhibiting Thrombolytic Effect for P6A and Its Analogs. Biochem. Cell Biol.. 2007,85:730-740.SCI 4. Keli Gu, Lanrong Bi, Ming Zhao, Chao Wang, Cheryl Dolan, Michael C. Kao, Jeffrey B.-H. Tok and Shiqi Peng*.Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes. Bioorg. & Med. Chem. 2006,14:1339－1347.SCI 5. Ming Zhao, Lanrong Bi, Wei Bi, Chao Wang, Zhe Yang, Jingfang Ju and Shiqi Peng*..Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity. Bioorg. & Med. Chem. . 2006,14:4761-4774.SCI 6. Ming Zhao, Lanrong Bi, Wei Wang, Chao Wang, Michèle Baudy-Floc’h, Jingfang Ju, Shiqi Peng*..Synthesis and cytotoxic activities of β-carboline amino acid ester conjugates. Bioorg. & Med. Chem. . 2006,14:6998-7010.SCI 7. Yihui Wu, Lanrong Bi, Wei Bi, Zeng Li, Ming Zhao, Chao Wang, Jingfang Ju, Shiqi Peng*..Novel 2-Substitutednitronyl Nitroxides as Free Radical Scavengers: Synthesis, Biological Evaluation and Structure- Activity Relationship. Bioorg. & Med. Chem. 2006,14:5711-5720.SCI 8. Lanrong Bi, Yue Zhang, Ming Zhao, Chao Wang, Priscilla Chan, Jeffrey B.-H. Tok, Shiqi Peng*.Novel Synthesis and Anti-inflammatory Activities of 2,5-disubstituted-dioxacycloalkanes. Bioorg. & Med. Chem. 2005,13:5640－5646.SCI 9. Ming Zhao, Junling Liu, Chao Wang, Lili Wang, Hu Liu, Shiqi Peng*.Synthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides. J Med. Chem. 2005,48:4285-4292.SCI 10. Ming Zhao, Chao Wang, Yanfen Wu, Kexiang Zhou, and Shiqi Peng*.Synthesis and Thrombolytic Activity of Carboline-3-carboxylic Acid Modified Metabolites of ARPAK. Preparative Biochemistry & Biotechnology. 2004,34:55-74.SCI 11. Ming Zhao, Chao Wang, Shiqi Peng*.The composition and sequence specificity of Pro-Ala-Lys-OH for the throm- bolytic activities of P6A and related oligopeptides. Bioorg. & Med. Chem. 2004,12:2275-2286.SCI 主编或副主编的著作/译著 重要奖项 1. 治疗中风和骨质疏松多肽的关键技术研究 北京市科技进步贰等奖 2005 2. 新型口服重金属驱排立得益片 四川省科技进步叁等奖 2003 3. 基于氨基酸的寡肽活性物质研究 北京市科学技术进步二等奖 2001 4. 基于氨基酸的杂环药物先导结构的研究 中国高校科技进步贰等奖 2001